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הפטיטיס ובעיות כבד
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בד"כ רצוי לעבור איבחון דרך "עיניים סיניות" ואז ניתן לאפיין את הבעיה כפי שמתבטאת באופן אישי. האבחנה האישית תאפשר בניית תערובת צמחים סינית יעילה ומדוייקת. ( ראה תוצאות בדיקות בכפתור מימין)
 
אולם, ברשותינו הרכב צמחים יעיל ביותר ולהלן מידע מפורט אודותיו:
 
 
                                              LV DETOX      ההרכב  מכיל :
 jin qian cao
da huang
 zhi zi
chai hu
huang qin
 long dan cao 
   צמחים יעילים להפטיטיס, הורדת רעילות, הנעת QI וניקוי חום.   פעולה: הצמחים מנקי ליחה דלקת ורעילות מהכבד.
 הניקוז הינו דרך הצואה בד"כ ומעט דרך השתן. לכן יש לצפות לשינויים בשתן ובצואה.     
     ישנה גם פעולת חיזוק של הטחול והקיבה, הרגעת הלחץ בכבד, ופירוק הצטברויות בו.  
מצורף חומר מקצועי לעיונכם כולל המרשם המקורי כפי שנרשם ע"י אחד המומחים הגדולים בעולם להפטיטיס.
The study on the antioxidative effect of yin chen hao tang

  Organization: Tainan Municipal Hospital

  Auther: Ming-feng Chen

  In our previous study, we found that Inchenhau-Tang(ICHT) is a most strong anti-oxidant among twelve herb drug prenoiptions which are popularly used in treatment of liver disease. ICHT is mostly used in treatment of acute hepatitis with jaundice. Therefore, in this study we further investigated the scavenging effect of ICHT on the oxygen radicals including superoxide anion(O2() and hydrogen peroxide(H2O2) in the whole blood of patients with acute hepatitis. On the other hand, we also investigated the anti-oxidative effect of Artemisiae Capillaris Herba(ACH), Gardeniae Fructus(GF), and Rhei Rhizoma(RR) which are composed of ICHT. The results show that, the watery extract of ICHT significantly scavenged both superoxide anion and hydrogen peroxide in the whole blood of patients with acute hepatitis. The scavenging effect of ICHT on superoxide anion was greater than that on hydrogen peroxide. On the other hand, all of watery extracts of three composed herb drugs significantly scavenged superoxide anion produced by xanthine/xanthine oxidase, and markedly inhibited the production of lipid peroxide from rat liver cells induced by FeCl2. Among them, RR had most strong anti-oxidative effect. The above results revealed that watery extract of ICHT can scavenge oxygen radicals in the whole blood of patients with acute hepatitis. Among three composed herb drugs of ICHT, RR is a most important antioxidant.

  Key words: Inchenhau-Tang, antioxidative effect, acute hepatitis, superoxide anion, hydrogen peroxide, lipid peroxide
 
 
Yin Chen Hao Tang
Professional Data
 Function
Ingredients
 Yin Chen
 Zhi Zi
 Da Huang
Dosage Info
Decoct Yin Chen first, then Da Huang. Remove dregs. 1 dose a day, divided into three administrations. 5:1 concentrated extract: 9 grams/day.
Yin Chen Hao Tang functions to remove heat and dampness and eliminate jaundice. It is primarily used to treat the following conditions: jaundice due to damp heat, yellowish pigmentation all over the body (in particular, on the face), slight abdominal fullness, mouth dryness without feeling of thirst, difficulty in urination or cloudy urine, tongue coated with heavy yellow fur, pulse that is either deep and rapid or slippery and rapid.
 Precautions Back to Top
Side Effects: Literature has reported one case of acute gastritis as a result of taking Yin Chen Hao Tang.(1)
 Pharmacology Back to Top
Protecting the liver: Administered to mice with liver damage caused by D-aminogalactose and lipopolysacchride, ethanol-based extract of Yin Chen Hao Tang can significantly dampen the activity of glutamic-pyruvate transaminase in the serum, lower the level of glutathione-S-epoxida-transferase, and decrease the content of lipo-peroxides in the liver homogenate. At the dosages of 4g/kg, 6g/kg, and 9g/kg, the formula can reduce the serum ALT level in mice with immunological liver damages caused by BCG and lipopolysaccharide. At 6g/kg and 9g/kg, it can increase the level of reduced glutathione in the liver homogenate.(2)
Effects on the release of NO by macrophages: Experiments show that Yin Chen Hao Tang’s ethanol-based extract (0.2-20mg) can inhibit NO from being generated by cultivated peritoneal macrophages of mice. At 100, 150, and 200 minutes, mouse serum containing Yin Chen Hao Tang’s ethanol-based extract can promote the formation of NO by macrophage, and this effect peaks at the 100-minute mark.(3)
Lowering the blood lipid level: Fed to mice of moderately high cholesterol levels, Yin Chen Hao Tang can significantly decrease the serum levels of total cholesterol (TC), triglycerides, LDL-cholesterol, the LDL-C/HDL-C ratio, increase the HDL-C/TC ratio, and decrease the LDL-C/HDL-C ratio. No pathological yellowish spot or plague is found on the blood vessel wall and only slight lipid deposition is found in the visceral organs.(4)
Anti-inflammatory and tranquilizing effects: At 3.0g/kg and 1.00g/kg, Yin Chen Hao Tang can significantly inhibit acetic acid-induced increase in vascular permeability in mice. The inhibition rates are 41.2% and 22.0% at the two dosage levels, respectively. It can also inhibit carrageenin-induced pad edema in rats, with inhibition rates of 50.1% and 13.7%, respectively. Inhibition of acetic acid-induced body twisting in mice and rat pad edema at rates of 59.8% and 37.5%, respectively.(5)
Cholagogic effect: Administered to hamsters by endogastric infusion for 30 days, a modification of Yin Chen Hao Tang is shown to inhibit the formation of cholelithiasis. The same formula also suppresses changes in the gastric atrium caused by gall system diseases, indicating a protective effect for the gastric mucosa.(6)
Anti-tumor effects: Experiments show that Yin Chen Hao Tang has a dose-dependent inhibitory effect on sodium nitrite- and N-methylbenzethonium-induced pathological hyperplasic changes to the gastric atrium and the esophageal epithelium in mice, indicating that the formula can block the tumogenic action of sodium nitrite and N-methlbenzethonium, and therefore increasing the cellular immunological function.(7)
Effects on the fluidity of cell membrane: In the early stage of pancreatitis, the fluidity of pancreatic cell membrane, mitochondrial membrane and lysosomal membrane decreases significantly. Yin Chen Hao Tang and its ingredients Da Haung (Rhubarb) and Zhi Zi (Gardenia) are shown to normalize the fluidity. Specifically, Da Haung (Rhubarb) and Zhi Zi (Gardenia) are shown to increase the fluidity of cell membrane, mitochodrial membrane, lysosomal membrane, and Yin Chen Hao Tang is shown to increase the fluidity of lysosomal membrane.(8)
 
 Clinical Application Back to Top
Jaundice-type Hepatitis
Yin Chen Hao Tang was used to treat 50 cases of acute jaundice-type hepatitis. Modifications were made according to symptoms. After 3 courses of treatment, 47 cases recovered, 2 cases improved, and 1 case did not respond to the treatment, with a total effective rate was 98%.(9)
A modification of Yin Chen Hao Tang was used to treat 122 cases of juvenile jaundice-type hepatitis. The results: 100 cases recovered, 20 cases significantly improve, and the remaining 2 cases improved, with a total effective rate of 100%.(10)
Hepatitis A
One hundred and eighty cases of juvenile hepatitis type A were treated with a modification of Yin Chen Hao Tang. The modifications of the formula were as follows: for patients with fever, Chai Hu (Bupleurum) and Huang Qin (Scutellaria) were added to the basic formula; for patients suffering from nausea and vomiting, Sha Ren (Glehnia Root) and Huo Xiang (Agastache) were added; for patients with epigastric fullness, Hou Bu (Magnolia Bark) and Zhi Qiao (Aurantium Fruit), among others, were added; for patients with poor appetite, Jiao San Xian (a mixture of Mai Ya (Malt)), Shan Zha (Crataegus), and Shen Qu (Medicated Leaven)) were added; for patients with yellowish urine, Mu Tong (Akebia) was added; and for patients with high levels of glutamine transferanse, Wu Wei Zi (Schizandra) was added in large dose. The formula was administered daily, spread out in frequent doses throughout the day. The results: 5 cases recovered after 3 doses, another 56 cases recovered after 7 doses, and the remaining 119 cases recovered after 12 doses.(11)
Hepatitis, other than Type A or B
Forty-two cases of hepatitis of neither type A nor type B were treated with Yin Chen Hao Tang. The results: 13 cases recovered, 26 cases improved, and the remaining 3 cases did not respond to the treatment, with a total effective rate of 92.86%.(12)
Hepatitis E
A modification of Yin Chen Hao Tang was used to treat 20 cases of jaundice-type hepatitis infected by hepatitis virus E. The modified formula consisted of Yin Chen (Oriental Woodworm), Zhi Zi (Gardenia), Long Dan Cao (Gentiana Root), Jin Yin Hua (Lonicera Flower), Fu Ling (Hoelen), Ze Xie (Alisma), Da Huang (Rhubarb), Ji Nei Jin (Membrane of Chicken’s Gizzard), Ban Lan Gen (Isatis Root), and Shan Zha (Crataegus). One dose of the formula in decoction, divided into three separate administrations, was taken daily. The results: all 20 patients recovered after being treated for 1-2 months.(13)
Chronic Cholangitis
Thirty-eight cases of chronic cholangitis were treated with Yin Chen Tao Tang plus Chai Hu (Bupleurum) and Chi Shao (Peony Red). The results: 9 cases resolved, 12 cases significantly improved, 13 cases improved, and the remaining 4 cases did not respond to the treatment, with a total effective rate of 89.47%.(14)
Primary Hepatoma
Yin Chen Hao Tang was used to treat 48 cases of fever after embolization and chemotherapy for primary hepatoma. Modifications were made according to the patient's symptoms. The results: 31 cases significantly improved, 11 cases improved, and the remaining 6 cases did not respond to the treatment, with a total effective rate of 87.5%.(15)
 
 

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